The Hidden Link Between IBS, Inflammation and Mental Fog

Increasing evidence suggests that low-grade immune activation in the gut can influence brain signaling, leading to symptoms such as fatigue, brain fog and mood changes which are often present in disorders of brain gut interactions. The biggest mediator behind these outcomes? The brain gut microbiome system: a bidirectional communication system highly susceptible to immune dysregulation, with mast cells, cytokines and the vagus nerve being key players in this process.