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Explore Gut Health Insights With Dr. Mayer

This is your access to a wealth of resources that explore the latest research, practical tips, and inspiring stories related to the mind-gut connection.

Whether you’re looking for informative articles or engaging conversations, this section is designed to enrich your understanding and empower you on your journey to better health. Tune in or read on to discover how nurturing your gut can lead to profound improvements in your overall wellbeing.

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Dr. Emeran Mayer introduces The Mayer Model, the book he has been working toward for 45 years. He explains why his earlier work focused on the science of brain-gut communication, why this book is built for application.
Dr. Emeran Mayer examines a new analysis from the Global Burden of Disease project, published in Lancet Public Health, that measures the growing gap between how long we live and how long we live well.
Dr. Erin Mauney, a pediatric gastroenterologist and researcher at Harvard and Massachusetts General Hospital, talks about one of the first clinical trials of psilocybin-assisted therapy for patients with treatment-resistant IBS.

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Is There a Link Between Fungi in the Gut and ADHD in Kids?
Most microbiome research stops at bacteria, but a Taiwanese team looked at the fungi instead and found a clear difference between children with ADHD and healthy controls. One yeast species showed up in higher numbers in the ADHD group, and what its secretions did to cultured intestinal cells points to a mechanism worth understanding. A separate study found gut bacteria in ADHD patients producing more of a specific neurotransmitter’s building blocks, with brain scans showing an unexpected effect….
How Obesity Can Impact Your Brain Health 
Fat tissue behaves differently depending on how much of it there is, and in lean people it does something most readers would not predict. Researchers feeding fruit flies a high-sugar diet found the brain’s cleanup crew stopped doing its job, which explains more about cognitive decline than weight alone ever could. Not everyone carrying excess weight develops neurodegenerative disease, and the exceptions may tell us as much as the rule….
Are Changes in the Gut Microbiome Associated with the Development of Cancer?
Of the roughly one trillion microbial species on Earth, only eleven are known to cause cancer, and together they account for a striking share of cases worldwide. One bacterium injects a toxin directly into the cells lining the stomach, and what that toxin switches off is the reason it carries the strongest known risk for gastric cancer. Comparing the microbiomes of people with and without cancer cannot tell us which came first, and the piece is direct about what that limitation means….

Read Dr. Mayer's Articles

What We Have Learned About Microplastics and Health So Far in 2026
The two everyday exposures that predicted who carried the most plastic in their blood. What happened to the liver when microplastics met a high-fat diet. Why one of the most widely shared plastic-in-the-brain headlines was probably overblown…
Eating With Others Might Do More for Your Mental and Physical Health Than You Think
Why living under the same roof as your family may not protect your mood the way you’d expect. The two questions Gallup added to a 150,000-person global survey, and the well-established predictors of wellbeing they went head to head with. What shows up on brain scans of older adults who eat alone, and why better diet quality doesn’t fully account for it….
Is Chronic Inflammation Really Behind Heart Disease?
A drug that shut down inflammation exactly as designed, in 6,300 patients, and what it did to their heart attacks and strokes. Why the same theory has now produced both convincing wins and outright failures, sometimes with the same drug in the same kind of patient. What all of this means for the claim that one process quietly drives heart disease, dementia, and colon cancer alike….

Dr. Mayer's Guest Appearances

How Does The Gut-Brain Connection Work?
The Liz Moody Podcast
StarTalk with Neil Degrasse Tyson
The Goop Podcast with Gwyneth Paltrow