How Does The Gut-Brain Connection Work?

Gut feelings, trusting your gut, butterflies: We have lots of expressions about how our brains and our bowels are intertwined. But how well do we understand the science of this on the biomolecular level? And which of those organs is actually in the driver’s seat? Flora churned through the details with neurogastroenterologists Emeran Mayer and Trisha Pasricha on stage at the 2026 Aspen Ideas Festival in Colorado.