The Mitochondrial Key to Longevity, Stress, & Holistic Health with Martin Picard, PhD

Dr. Emeran Mayer and mitochondrial biologist Martin Picard, PhD, explore how mitochondria and the gut microbiome shape energy, stress, mental health, and resilience, offering a new paradigm for understanding true well-being.

Martin explains how mitochondria, far beyond their reputation as the “powerhouses of the cell”, act as dynamic regulators of energy, resilience, and even emotion. He explores their deep evolutionary connection with the gut microbiome and how this relationship shapes inflammation, mental health, and overall well-being.

You’ll also hear about Martin’s concept of “intrinsic health,” a field-like state that brings together systems biology, human experience, and the flow of energy. Together, he and Dr. Mayer reflect on why stress can deplete our energy reserves, how consciousness may be more fundamental than matter itself, and why a holistic perspective is essential for understanding true health.
Key Topics Covered:

• The evolutionary story of mitochondria and their partnership with the gut microbiome
• Why energy is best understood as flow rather than a fixed resource
• The role of stress in depleting energy and resilience
• How intrinsic health integrates biology and lived experience
• A new paradigm for understanding mental and physical well-being

Discover how mitochondria and the microbiome together form the foundation of vitality, and why embracing a holistic approach to energy and health may transform the way we think about well-being.