Another tumultuous year has come to an end, and based on most people’s gut feelings, there have been more things to worry and be upset about than to celebrate in 2023. During this last year, we have discussed many of these topics in this blog. Rising rates of diabetes, metabolic syndrome, obesity, colon cancer and inflammatory bowel disease affecting younger age groups, chronic pain conditions, the opioid crisis, the Covid-19 pandemic, poor gut health, poor dietary habits, accelerating climate change, dramatically increased numbers of migrants on our borders, political polarization and a world-wide rightward shift in Western political systems, wars in Ukraine and the Middle East are just some of the negative news that we are bombarded with in the social media on a daily basis generating a constant state of stress and anxiety.
“…there is little indication that the unfolding polycrisis causing chronic persistent stress and driving this unhealthy emotional state, will improve any time soon or suddenly disappear.”
Anxiety levels amongst Americans, in particular younger people have gone through the roof, and there is little indication that the unfolding polycrisis causing chronic persistent stress (referred to as allostatic load), and driving this unhealthy emotional state, will improve any time soon or suddenly disappear. The term polycrisis has been defined by the Cambridge dictionary “as a time of great disagreement, confusion, or suffering that is caused by many different problems happening at the same time so that they together have a very big effect.”
“… there are 3 different types of psychological stress”
However, it is important to differentiate between at least 3 different types of psychological stressors:
“If two individuals are exposed to the same type and severity of stress, it is the interindividual difference in this subjective threat assessment that determines how much cortisol and norepinephrine an individual produces.”
If two individuals are exposed to the same type and severity of stress, it is the interindividual difference in this subjective threat assessment that determines how much cortisol and norepinephrine that individual produced, to what degree our immune system is engaged and to which degree pain facilitatory mechanisms are recruited to increase pain sensitivity. We know many of the factors that underlie this increased stress perception/responsiveness, ranging from genetics, adverse early life events, lack of resilience mechanisms, and lack of a social support system. It is primarily the subjective stress sensitivity which is enhanced to a significant degree by the bombardment with negative news, and which has been identified as the cause for negative mental and physical health consequences.
“…we can greatly change the way we perceive and respond to the 24-hour daily negative news cycle”
Fortunately, it is also the subjective nature of the personal stress responsiveness that provides us with a way to deal with the unfolding polycrisis. While it is very limited what a person can do to combat climate change, to prevent mass extinction, or to slow the epidemic of chronic noncontagious diseases, we can greatly change the way we perceive and respond to the 24-hour daily negative news cycle:
Here are a few health related examples of such positive news to get started with: The successful recovery from the COVID-19 pandemic, the continuous increase in longevity as documented by the number of centenarians in the US, the success in our fight against many cancers, which have turned breast cancer and some forms of melanoma from a death sentence to a chronic disease, the development of new medications to treat obesity and its metabolic complications, which have the potential to combat our chronic disease epidemic, and the recent introduction of a vaccine that for the first time is able to prevent malaria.
And last but not least, there is reason to celebrate the unfolding paradigm shift in the West, from a reductionistic, linear understanding of the world which has gotten us into all the unfolding crises, to one of interconnectedness of all systems, ranging from the invisible microbes in the soil, to human and planetary health. Like a massive aircraft carrier, it may take a while to turn around our obsolete Western world view around, but I am convinced that this paradigm shift will eventually get us out of our current dilemma. This is definitely a goal to invest our energies in!
Let’s celebrate this positive news, embrace the paradigm shift wherever we see it, and take simple actions, instead of ruining our health by seeing the world with the eyes of attention-catching news networks creating anxiety, worry and fear!

Emeran Mayer, MD is a Distinguished Research Professor in the Departments of Medicine, Physiology and Psychiatry at the David Geffen School of Medicine at UCLA, the Executive Director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience and the Founding Director of the Goodman-Luskin Microbiome Center at UCLA.