Interview with Dr. David Perlmutter: Diet and The Mind Gut Connection


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I recently was invited by Dr. David Perlmutter for an interview on my upcoming book The Mind-Gut Connection. Don’t forget to watch it when it becomes available on his website on July 9. Late last year, I was invited to speak at the Integrative Healthcare Symposium organized by Dr. Perlmutter in Hollywood, Florida, Oct 9-10, 2015, a gathering of several hundred people interested in Functional Medicine, diet and brain health. Functional Medicine has become a “parallel universe” to modern medicine, which is unknown to the majority of my colleagues. I was amazed about the interest of the audience in the topic of the brain-gut-microbiome axis, and the role of the gut microbiota in our health.

foodDr. Perlmutter has written the best selling books Grain Brain and Brainmaker in which he discusses eloquently the impact that diet can have on our brain health. While I disagree with some of Dr. Perlmutter’s specific dietary recommendation, he has to be congratulated for bringing the brain-gut-microbiome axis, and the detrimental effect of the modern North American diet in these interactions, onto center stage. My own views on the health benefits of a high fat diet and the detrimental effect of gluten on our brain health differ somewhat from Dr. Perlmutter’s views. However, in the field of diets there has always been a healthy amount of controversy and disagreement. Furthermore, Dr. Perlmutter is a neurologist who has developed a strong interest in the gut, and I am a gastroenterologist who is interested in the brain. I have studied the interactions between the brain, the gut and its microbiome for some 30 years and I believe my views on the topic are firmly based on clinical experience and available science. Much of this science remains to be discovered.

If you would like to know more about my own views on the brain-gut-microbiome axis, check out my upcoming book The Mind Gut Connection on Amazon), listen to some key messages from my book on, or view the interview with Dr. Perlmutter on

Here is what Dr. Perlmutter had to say about my book:

“Dr. Emeran Mayer exquisitely leverages the leading edge of neuroscience that links all manner of brain function to what goes on in the digestive system. The Mind-Gut Connection presents the incredibly humbling reality that our very perception and interpretation of the world around us is virtually dictated by the microbes living within us. This book redefines what it means to be healthy and eloquently provides the means to manifest that goal.”

Order the book today on Amazon.

Watch the interview:

Emeran Mayer, MD is a Distinguished Research Professor in the Departments of Medicine, Physiology and Psychiatry at the David Geffen School of Medicine at UCLA, the Executive Director of the G. Oppenheimer Center for Neurobiology of Stress and Resilience and the Founding Director of the Goodman-Luskin Microbiome Center at UCLA.